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Croma's complementary and synergistic portfolio is designed to address diverse skin needs, with all their products supported by robust research demonstrating proven safety and efficacy. Hyaluronic Acid and Polynucleotides each provide targeted action on fibroblasts and the surrounding extracellular matrix (ECM), promoting skin regeneration. Clinical trials have shown both treatments to be well tolerated, with no reports of severe adverse events.
REFINE with croma revitalis® (non cross-linked filler),
ENHANCE with saypha® lips (cross-linked HA),
and REJUVENATE with PolyPhil™ (hybrid/polynucleotides).
croma revitalis® is a non cross-linked filler that replenishes the loss of hyaluronic acid due to ageing, boosting hydration, improving the skin’s tone and elasticity, and filling fine lines and wrinkles.
saypha® lips is a cross-linked hyaluronic acid dermal filler for lip augmentation that expertly restores volume. As it’s designed with more elastic than viscous properties, it effectively maintains its shape against the dynamic forces associated with lip movement, ensuring long-lasting, safe, and predictable lip fullness.1
PolyPhil™ and PolyPhil™ next restore skin elasticity and promote hydration2,3 by stimulating the body’s own cell regeneration. Used as a foundation therapy, PolyPhil™ also creates better outcomes for further aesthetic treatments.2
1. Müller et al. (2024) - Aesth Surg J.
2. Cavallini M, Papagni M. Long Chain Polynucleotides Gel and Skin Biorevitalization. International Journal of Plastic Dermatology-ISPLAD. 2007;
3 (3): 27-32. 3. Manufacturer data on file.
What the Healthcare Practitioner's say:
The enchantment of croma revitalis® rests in its ability to revitalise the delicate areas around the eyes and mouth, where fine lines often betray age first.
As we age, our skin loses vital components such as hyaluronic acid and collagen, resulting in sagging and creases. croma revitalis® remedies this by delivering intense hydration deep into the skin, elegantly smoothing out superficial wrinkles.
Yet, the appeal of this product goes beyond hydration—it imparts a youthful glow and firm resilience that many covet. By directly addressing the reduction in quality and quantity of essential dermal cells, this pioneering treatment redefines facial rejuvenation, offering a refined approach to skin enhancement.
Alexandra Mills
"The diverse indications and benefits of the PNHPT ® technologies are widely reported, which includes promoting hydration and scavenging of free radicals, enhancing collagen synthesis, as well as increasing the number and viability of fibroblasts.
It is increasingly recognised that combined modalities synergise and maximise treatment outcomes, often prolonging results, whilst addressing multiple aspects of ageing. A combination treatment approach holistically supports a long-term journey, whilst reinforcing a natural and patient-centred approach, and is a central part of my clinical practice.
Combining linear / non-cross linked hyaluronic acid (HA) alongside PN-HPT® can deliver natural and targeted results by refining localised areas of concern as well as achieving global improvements in skin quality, particularly around the perioral and periocular areas, which truly maximises the treatment outcomes."
Anna Baker
