New Croma PhilArt and PhilArt eye

With the launch of PhilArt, a complete series of injectable skin boosters, Croma has broadened its already comprehensive portfolio. Skin boosters are an important pillar of a minimally invasive aesthetics portfolio, next to hyaluronic acid fillers, botulinum toxin and PDO threads, allowing for combination therapies and a full-face approach.

New Croma PhilArt works by stimulating the body’s own cell regeneration, and improves patients’ skin quality by rejuvenating the skin and making it more radiant. The PhilArt range also restores the skin’s elasticity and promotes hydration. The application ranges from the face, scalp and neck to the décolletage and hands.Used as a foundation therapy, it also creates better outcomes for further aesthetic treatments.

Polynucleotides
PhilArt is an injectable gel consisting of long-chain polynucleotides, which injectables promote hydration of the skin and scavenge free radicals, thereby building an optimal environment for the growth of fibroblasts (cells that produce collagen). As a consequence, they promote the production of new collagen and elastic fibres, stimulating the body’s own cell regeneration.

Based on natural ingredients
The polynucleotides are of natural origin and derived from European freshwater fish intended for human consumption. The manufacturing process is based Croma-Pharma expands its aesthetic portfolio with the launch of injectable polynucleotides biostimulators on the polynucleotide high purification technology (PN-HPT), leading to a superior level of purification, thus ensuring product safety.

Proven safety and efficacy
Polynucleotides have a proven safety and efficacy profile with high tolerability and low risk of adverse events, supported by extensive clinical data. Their use is based on more than 70 years of research and more than 100 published studies presented at national and international congresses.



All skin types and age groups
PhilArt offers a line of four injectables, suitable for all skin types and age groups. Croma launched the first two products, PhilArt and PhilArt Eye at the IMCAS World Congress at the end of January 2023. PhilArt is an injection treatment for more radiant and rejuvenated skin in young and mature patients, for use on the face, neck, décolletage and hands.
PhilArt Eye is an injection treatment for the delicate area around the eyes to revive tired-looking eyes, for young and mature patients. PhilArt Hair and PhilArt Next will follow in Q2 2023.



PhilArt Skin Enhancement Technique (SET)
Optimise patients’ skin for enhanced results with other aesthetic treatments
PhilArt Skin Enhancement Technique (SET) is the basic treatment enabling natural restoration for optimal skin conditions and therefore enhancing other aesthetic treatments.
Infiltration with polynucleotides restores elasticity, hydration and trophism to all types of skin, regardless of age.
SET has an important role for the skin quality, restoring radiance and youthfulness, promoting regeneration and reducing wrinkles and laxity.
SET generates a synergistic effect with other aesthetic procedures, such as laser, radiofrequency, fillers, peeling, needling and surgery.


References
1. Bartoletti E, Cavallini M, Maioli L, Massirone A, Palmieri IP, Papagni M et al. Introduction to Polynucleotides Highly Purified Technology. Aesthetic Medicine. 2020 Oct-Dec; Vol.7 (1): 43-47.
2. Collangelo MT. Govoni P, Beletti s, Squadrito F, Guizzardi S, Galli C. Polynucleotide biogel enchances tissue repair, matrix desposition and organization. J. of Biological Regulators & Homeostatic Agents. 2021; Vol.35 (1): 355-362.
3. Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M et al. Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine. J Cosmet Dermatol. 2021 Mar. 20 (3): 922-928. doi: 10.11.11/jocd.13679. Epub 2020 Sept. 21. PMID: 32799391; PMCID: PMC7984045.
4. Cavallini M, Papagni M. Long Chain Polynucleotides Gel and Skin Biorevitalization. International Journal of Plastic Dermatology-ISPLAD. 2007; 3 (3): 27-32.
5. Massirone A. Polynucleotides Highly Purified Technology and the face skin, a history of innovative skin priming. Aesthetic Medicine. 2021 Jan-Mar; Vol. 7 (1): 25-40.
6. Araco A, Araco F. Preliminary Prospective and Randomized Study of Highly Purified Polynucleotide vs Placebo in Treatment of Moderate to Severe Acne Scars. Aesthet Surg J.
2021 Jun. 14; 41 (7): NP866-NP874. doi: 10.10.93/asj/ sjab125. PMID: 33755110. PADB1222IMCAS | 38942 Product information for healthcare professionals
7. Manufacturer data on file
8. PhilArt Instruction for use