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During the winter season, skin is exposed to a combination of low humidity, harsh outdoor elements and indoor heating—which can accelerate transepidermal water loss, increase inflammation, cause dryness and compromise skin. Skin can lose more than 25% of its ability to hold moisture in the winter, making it feel dryer and tighter and patients can also notice that their skin seems more prone to dryness and ‘tightness’ as they age due to the decrease of water content in the stratum corneum, which decreases with age.
Profhilo HAENKENIUM is a topical formulation which provides immediate skin hydration, natural antioxidant protection, as well as long term accumulative skin rejuvenation results. Containing Salvia Haenkei patented extract: HAENKENIUM and an innovative hyaluronic acid (HA) complex—Profhilo HAENKENIUM is more than just a moisturiser and also acts as a gerosuppressant agent, providing protection from free radicals, a cause of oxidative stress and premature cellular senescence. Cellular senescence is a process that puts a stop to the cell cycle in response to various stressors and has emerged as a potential contributor to ageing and age-related disease. Salvia Haenkei extract was shown to decrease senescence by 50%, bypassing the cellular growth arrest induced by PTEN loss*.
The protective strength of this formulation as a natural antioxidant also makes it suitable for use post treatment after dermoaesthetic treatments such as peels, dermal fillers, micro-needling, and other treatments to soothe irritated skin, whilst restoring the normal levels of hydration to the skin.
Developed by IBSA, one of the leading pharmaceutical companies in hyaluronic acid production, Profhilo HAENKENIUM optimises skin cell health, improves the lipid layer, reduces the intracellular level of free radicals (ROS) and can be used alongside the Profhilo injectable treatment or alone as a skin health topical treatment for patients wanting to optimise skin cell health.
Ideal for the face, neck and décolletage, Profhilo HAENKENIUM can be used on a daily basis morning and night or as advised by a practitioner.
What does Profhilo HAENKENIUM do?
• Provides an exceptional antioxidant effect by reducing the intracellular level of free radicals (ROS).
• Protects the skin from premature ageing caused by oxidative stress factors (i.e. pollution, diet, smoking).
• Prevents photoageing counteracting damage from UV exposure.
• Restores barrier function and skin hydration counteracting the physiological reduction of HA.
• Alleviates skin irritation and redness caused by oxidative stress, sensitisation factors or following dermoaesthetic treatments.
• Diminishes visible signs of ageing such as small wrinkles, while restoring skin firmness, elasticity and tone.
Clinical results
The trial consisted of evaluation of 50 patients undergoing topical treatment with Profhilo HAENKENIUM twice a day (morning and evening). All results showed a statistically significant improvement at the first control visit (14 days)*:
• 43.2% increase in antioxidant activity
• 10% reduction in wrinkle depth
• 3.3% increase in cutaneous elasticity
*Alimonti A et al. Identification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assay. Aging (Albany NY) 2016; 8(12):3223-36
*IBSA Internal Date on file 2018
